fenbendazole for pancreatic cancer Fenben is a commonly used dewormer that was recently linked to the curing of cancer in a US man named Joe Tippens. Tippens claims that taking fenbendazole along with a variety of other supplements cured his cancer, and the claim has spread worldwide. However, a specialist cancer information nurse tells Full Fact that there is insufficient evidence that fenbendazole can cure cancer and that the drug has not been tested in clinical trials in humans.
The objective of this study was to investigate the ways that lung cancer patients acquire fenbendazole information and how they perceive that information. This was done through semi-structured interviews conducted with seven lung cancer patients in a hospital. The interviewees were ages 56 to 75 and had been diagnosed with lung cancer from three months to five years ago.
Participants were asked to talk about their process of acquiring fenbendazole information and general cancer information on a daily basis. They were also asked to discuss the quality of the information they received and how they perceived it.
A cellular pleiotropic effect of fenbendazole was observed in colon cancer cell lines and patient-derived colon cancer organoids, suggesting that it may inhibit tumor growth through multiple pathways. It also altered glucose uptake in NSCLC cells and inhibited the enzymatic activity of HKII, resulting in an increase in cell death. Furthermore, a fluorescence based competitive assay revealed that FZ binds to tubulin at the colchicine binding site, which could cause mitotic arrest and subsequent cell death.